COMPANY Data
My FAVORITES

Movers and SHAKERS
Wednesday, December 01, 2021
Lineage Cell Therapeutics (LCTX)
OpRegen Benefits Four Out Of Four Patients With Retinal Restoration
Lineage Cell Therapeutics is a clinical-stage biotechnology company developing novel cell therapies for unmet medical needs. Lineage’s programs are based on its robust proprietary cell-based therapy platform and associated in-house development and manufacturing capabilities. With this platform Lineage develops and manufactures specialized, terminally differentiated human cells from its pluripotent and progenitor cell starting materials. These differentiated cells are developed to either replace or support cells that are dysfunctional or absent due to degenerative disease or traumatic injury or administered as a means of helping the body mount an effective immune response to cancer. Lineage’s clinical programs are in markets with billion dollar opportunities and include three allogeneic (“off-the-shelf”) product candidates: (i) OpRegen®, a retinal pigment epithelium transplant therapy in Phase 1/2a development for the treatment of dry age-related macular degeneration, a leading cause of blindness in the developed world; (ii) OPC1, an oligodendrocyte progenitor cell therapy in Phase 1/2a development for the treatment of acute spinal cord injuries; and (iii) VAC, an allogeneic dendritic cell therapy platform for immuno-oncology and infectious disease, currently in clinical development for the treatment of non-small cell lung cancer. For more information, please visit www.lineagecell.com or follow the Company on Twitter @LineageCell.
Robert LeBoyer, Senior Research Analyst, Noble Capital Markets, Inc.
Refer to the full report for the price target, fundamental analysis, and rating.
Data From All Four Patient Show Improvements Lineage Cell reported new data from the fourth cohort in its Phase 1/2a clinical trial for OpRegen. The data is from the fourth patient in the cohort that received the highest quantity of OpRegen cells. The results showed restoration of cellular structure and functional improvement at 12 months. We believe this demonstrates tissue restoration and efficacy of the product.
Trial Was Designed To Show OpRegen Safety and Durability The OpRegen Phase 1/2a treated three cohorts of 12 patients to establish safety, then a fourth cohort of 12 patients to determine efficacy. In this fourth cohort, four of the patients had the majority of their lesions covered with OpRegn cells. The new data shows all four of these patients had cellular engraftment and visual acuity ...
This Company Sponsored Research is provided by Noble Capital Markets, Inc., a FINRA and S.E.C. registered broker-dealer (B/D).
*Analyst certification and important disclosures included in the full report. NOTE: investment decisions should not be based upon the content of this research summary. Proper due diligence is required before making any investment decision.
