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Renaissance in Inflammasome Therapeutics

Noblecon16  Panel is set to Discuss Recent Breakthroughs in Inflammasome Space

There is an ongoing renaissance in the potential for drugs targeting a unique inflammation hub, inflammasome. Inflammasomes are crucial to coordinate in?ammatory responses.  Inflammation is a protective immune response to harmful stimuli, such as pathogens, dead cells or irritants, and is tightly regulated by the host. The innate immunity is the first line of defense in recognition of infection and initiation of clearance by the host. The activation of the inflammasome is a key function mediated by the innate immune system. Three main domains comprise inflammasomes: sensor molecule, adaptor protein (ASC), and effector protein mainly pro-caspase 1.

Oligomerization (generation of multi-molecular complex of inflammasome) is triggered by danger associated molecular patterns (DAMPs) or pathogen-associated molecular patterns (PAMPs) that results in effector activation and leading to maturation of procytokines and pyroptosis, a form of inflammatory cell death. The nucleotide-binding domain-like receptor (NLR) family is the main group of proteins considered as inflammasome sensors. Inflammasome sensor proteins are involved in the recognition of particular danger stimulus and then initiate the assembly of inflammasome multimeric complex. Among NLR family (NLRs—NLRP1, NLRP2, NLRP3, and NLRC4, nonNLRs—absent in melanoma 2 (AIM2) and pyrin), NLRP3 recognizes the largest array of stimulus and it is the most studied in terms of developing NLR inhibitors. The adaptor proteins are known as apoptosis-associated speck-like protein (ASC) containing a caspase activation and recruitment domain (CARD). In response to PAMPs or DAMPs, the sensor molecule recruits ASC, which recruits pro-caspase 1. This interaction converts pro-caspase-1 into its activated form, caspase-1. Caspase-1 then cleaves the proforms of IL-1ß and IL-18 into their mature forms, which triggers the inflammatory process, which can induce cell death via a process known as pyroptosis (Exhibit 1). The release of IL-1ß and IL-18 leads to the activation of several downstream pathways that further assist in the inflammatory process.

Exhibit 1. The inflammasome mechanism of action

Source: Hoffman and Broderick, J Allergy Clin Immunol, 2016

While insufficient inflammation can lead to persistent infection of pathogens, excessive inflammation can cause chronic or systemic inflammatory diseases. Inflammasomes play a crucial role in mediating inflammation and therefore serve as potential drug targets for the treatment of inflammatory-mediated diseases. Inflammasomes have been associated with variety of autoinflammatory and autoimmune diseases, including neurodegenerative diseases (multiple sclerosis, Alzheimer’s disease, and Parkinson’s disease) and metabolic disorders (atherosclerosis, type-2 diabetes, and obesity). Currently, there are no approved inflammasome inhibitors; however, there are several early stage assets in the pipeline. While most companies are targeting the sensor molecule (NLRP3), some others are taking a unique approach targeting either the adaptor protein (ASC) or other molecules.

 

Exhibit 2. Recent selected deals in inflammasome space

At least, four biotechnology firms with NLRP3 inhibitors have been founded in the last four years. In 2018, they raised a collective $117 million in venture capital. Inflazome was recently granted over US$1M in funding from The Michael J. Fox Foundation for Parkinson’s Research (MJFF). High activity in inflammasome space was seen in the recent years. Among the multiple M&A and partnership deals, the majority of them were at preclinical stage. The transaction volume varied, $160 mm - $1.6 billion (Exhibit 2). Multiple acquisitions in the field show the first inflammasome target -NLRP3 -is gaining momentum. The question remains how fast the best set of indications can be identified from the sea of possibilities.

Selected Companies Targeting Inflammasome

Highlighted below the Inflammasome Panel attendees and selected companies with current programs in inflammasome therapeutics (alphabetical order).

Inflammasome Inhibitors: The Next Generation of Innovative Immunotherapy Agents
Monday, February 17 - 10:00am - 11:00am - Terrace Ballroom B

  • Paul Ashton, PhD., Co-Founder & CEO of Inflammasome Therapeutics, Inc.
  • Gary Glick, PhD., Co-Founder & Executive Chairman of IFM Therapeutics and Michigan Professor of Chemistry
  • Steve Glover, Co-Founder, President & CEO of Zyversa Therapeutics, Inc.
  • Robert W. Keane, PhD., Professor Physiology & Biophysics, Neurological Surgery & Microbiology, and Immunology at the University of Miami, and co-founder of InflamaCore, LLC
  • Clay B. Thorp, General Partner at Hatteras Venture Partners

IFM Therapeutics (Private company)

IFM Therapeutics (IFM) is a Boston-based, a privately held biopharmaceutical company focused on developing novel therapies that regulate the innate immune system. IFM was formed following the acquisition of the original IFM Therapeutics by Bristol-Myers Squibb in 2017 ($1.3 billion). IFM has a unique approach in regulating the management of its research and development activities. IFM has separate subsidiaries that are responsible for a particular set of programs. While each subsidiary is financially independent, they share common infrastructure and resources. IFM has established three subsidiaries: IFM Tre was launched in July 2018 and was subsequently acquired by Novartis in May 2019, IFM Due, which launched in February 2019, and the most recent, IFM Quattro launched in Dec 2019.

 IFM’s inflammasome platform is based on antagonists of NLR proteins for inflammation-mediated diseases (such as, Alzheimer’s, liver fibrosis/non-alcoholic steatohepatitis (NASH), and type 2 diabetes) and anti-cancer agents for modulating the tumor environment. IFM currently has two NLRP3 antagonists in the preclinical stage and one NLRP3 antagonist in Phase 1 for the treatment of inflammation, fibrosis, neuroinflammation. The rights of the above molecules belong to Novartis. IFM has another NLRP3 agonist, an anti-cancer agent, owned by Bristol-Myers Squibb.

Inflammasome Therapeutics (Private company)

Inflammasome therapeutics is developing therapies for Alzheimer’s, multiple sclerosis, macular degeneration, and type 2 diabetes by averting unusual inflammasome activation. They have identified and licensed a series of molecules known as Kamuvudines. The company has presented and published favorable preclinical data and recently established partnership with Boehringer Ingelheim to co-develop up to three therapies for patients with retinal diseases. Based on the agreement, Inflammasome is entitled to receive up to $160 million in up-front, research and development support and milestone payments and royalties based on future commercial sales of the products.

Inflazome (Private company)

Inflazome is a clinical stage biotechnology company that specializes in developing a NLRP3 small-molecule targeting inflammatory mediated diseases. The company received a grant in October 2019 from The Michael J. Fox foundation for the development of a NLRP3-specific Positron Emission Tomography (PET) tracer to allow non-invasive imaging of inflammasome-driven inflammation in the brain. Inflazome also completed a $46 million Series B funding in 2018. Inflazome’s lead asset Inzomelid is a potent, selective, brain penetrant NLRP3 inhibitor that is currently in Phase Ib trials. Inzomelid is indicated for the treatment of neuroinflammatory and neurodegenerative diseases such as Parkinson’s, Alzheimer’s and Motor Neuron Disease as well as the orphan disease CAPS. The second is Somalix, a potent, selective, peripherally restricted NLRP3 inhibitor that is currently in Phase I trials indicated for the treatment of arthritis and cardiovascular diseases. Clinical trial data are not available at this time.

Nodthera (Private company)

Nodthera is an early-stage biopharmaceutical company developing novel NLRP3 inhibitors for the treatment of NASH, pulmonary fibrosis, neurodegenerative disorders, and inflammatory bowel disease (IBD). The company’s lead candidate NT-0167 is currently under pre-IND stage. Nodthera completed a $40 million Series A funding in 2018.

Zyversa Therapeutics, Inc (Private company)

Zyversa is a clinical stage biopharmaceutical company developing first-in-class therapeutics for inflammatory (e.g., multiple sclerosis and NASH) and renal (e.g., diabetic nephropathy and lupus nephritis) diseases. Zyversa’s lead inflammasome targeting agent is IC 100, a monoclinal antibody targeting ASC for the treatment of multiple sclerosis. The company licensed IC 100 from InflamaCORE. Preclinical studies suggest that IC 100 inhibits the downstream inflammatory pathways. IC 100 is a nonspecific ASC inhibitor, which has a wide therapeutic range potentially inhibiting various types of inflammasomes. Zyversa has three additional ASC inhibitors under development for Lupus Nephritis, NASH, and diabetic kidney disease.



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  Release - Palladium One Mining (NKORF)(PDM:CA) - Closes $15 Million Bought Deal Financing, 02/24/2021
  Release - Comtech Telecommunications (CMTL) - Awarded Fast Tracking Ground Station Antenna System Contract from NASA, 02/24/2021
  Release - electroCore (ECOR) - Non-Invasive Vagus Nerve Stimulation Enters New Stage of COVID-19 Research, 02/24/2021
  What Percentage of U.S. Retail Sales is Ecommerce?, 02/24/2021
  Release - Onconova Therapeutics (ONTX) - Regains Compliance With Nasdaq Continued Listing Requirement, 02/24/2021
  Release - Comtech Telecommunications (CMTL) - Awarded $2.8 Million Contract for High-Power Amplifier Systems, 02/23/2021
  QuickChek - February 23, 2021, 02/23/2021
  Release - electroCore (ECOR) - Announces Two-Year Extension of gammaCore(TM) Listing in the NHS Supply Chain Catalogue, 02/23/2021
  Small Cap Names in a Big Crypto Market, 02/23/2021
  Release - Newrange Gold (NRGOF)(NRG:CA) - Newrange Intersects New High-Grade Gold Zone at Pamlico, 02/23/2021
  QuickChek - February 22, 2021, 02/22/2021
  Release - Comtech Telecommunications (CMTL) - Awarded Contract for 21.5m Radome from Commercial Space Company, 02/22/2021
  Release - Gevo (GEVO) - Gevo and Scandinavian Airlines System Amend $100 Million Fuel Agreement, 02/22/2021
  Managing Investment Portfolio Risk, 02/20/2021
  Cannabis Fundamentals Not Hype Important to Investors, 02/19/2021
  QuickChek - February 19, 2021, 02/19/2021
  Release - Kratos Defense & Security Solutions (KTOS) - Receives $55 Million C5ISR System Product Award, 02/19/2021
  Release - Ayala Pharmaceuticals Announces $25 Million Strategic Financing, 02/19/2021
  Release - Avivagen (VIVXF) - Announces the Publication of its New Zealand OxC-beta Livestock Dairy Trial, 02/18/2021
  Release - Chakana Copper (CHKKF)(PERU:CA) - Accelerates Drill Program With Second Rig, 02/18/2021
  Lithium-Ion Battery Recycling Market Heats Up, 02/18/2021
  Release - Comstock Mining (LODE) - Secures Majority Interest in Lithium-Ion Battery Recycling Company, 02/17/2021
  Massive power Outages and Extreme Weather Across Texas and the Midwest, 02/17/2021
  Release - Sierra Metals Inc. (SMT:CA)(SMTS) - Reports Q4-2020 Financial Results At Its Sociedad Minera Corona Subsidiary In Peru, 02/16/2021
  Can Mining be Green and Sustainable?, 02/16/2021
  Release - Idaho Champion Gold Mines Canada (GLDRF) - Reports Results of 2020 Core Drilling at Champagne Project Idaho, 02/16/2021
  Channelchek Virtual Road Show Series, 02/14/2021
  How did the Stock Market Perform Under Each President?, 02/13/2021
  The Business of Valentines Day, 02/12/2021
  Release - Ely Gold (ELYGF)(ELY:CA) - Acquires Heavy Rare Earth El Campo Project California, 02/12/2021
  Scientists Now Better Understand Viral Mutations, 02/11/2021
  Money Supply Drives Stock Market Performance, 02/10/2021
  Release - Comstock Mining (LODE) - Comstock and MCU Ready Launch of Mercury Remediation Operations, 02/10/2021
  Release - CoreCivic (CXW) - Announces 2020 Fourth Quarter Earnings Release and Conference Call Dates, 02/10/2021
  Release - CoreCivic (CXW) - Reports Fourth Quarter and Full Year 2020 Results, 02/10/2021
  Release - Chakana (CHKKF)(PERU:CA) - Intersects Highest Grade Interval To Date At Huancarama Soledad Project Peru, 02/09/2021
  Can Oil Prices Keep Climbing?, 02/09/2021
  Release - Golden Predator Mining (NTGSF)(GPY:CA) - Reports Final Drill Results from Brewery Creek Mine, 02/09/2021
  Release - Lineage Cell Therapeutics (LCTX) - Enters Into Exclusive Agreement With Neurgain Technologies To Evaluate Novel Delivery System For OPC1, 02/08/2021
  Technology Confounds Wall Street Pros, But Never for Long, 02/07/2021
  Seeking Alpha Paywall Causes Frustration, 02/05/2021
  Release - Comstock Mining (LODE) - Focuses on Climate Smart Mining, 02/04/2021
  Energy Outlook 2021, 02/02/2021
  Release - Ocugen (OCGN) - Announces Execution of Definitive Agreement for the Commercialization of COVAXIN, 02/02/2021
  Release - Stem Holdings (STMH) - Announces All Common Shares of DRVD will Trade Under symbol STMH on February 4 2021, 02/02/2021
  Release - Noble Capital Markets - Announces that RHK Capital will be Joining Noble, 02/02/2021
  Why is the Silver Price Rising?, 02/01/2021
  Release - Avivagen (VIVXF) - Announces Launch of Dr Tobias Beta Blend, 02/01/2021
  Class Action Lawsuit Against Robinhood, 02/01/2021
  Can Small Investors Compete With Wall Street?, 01/30/2021
  Release - CoreCivic (CXW) - Announces 2020 Fourth Quarter Earnings Release and Conference , 01/28/2021
  Release - Helius Medical Technologies (HSDT) - Announces Pricing of 9.6 Million Underwritten Public Offering Priced At Market, 01/28/2021
  Short-Sellers vs GameStop Buyers, 01/28/2021
  Release - Ely Gold (ELYGF)(ELY:CA) - Options Spanish Moon Project Nye County Nevada, 01/27/2021
  Release - Avivagen (VIVXF) - Announces Six Tonne Order of OxC-betaTM Livestock from New Customer in Mexico, 01/26/2021
  Release - Chakana (CHKKF)(PERU:CA) - Intersects 120.4m At Huancarama Soledad Project Peru, 01/25/2021
  Release - Golden Predator Mining (NTGSF)(GPY:CA) - Reports Brewery Creek Mine 2020 Drill Results, 01/25/2021
  Will Janet Yellen as Treasury Secretary be Good for Investors?, 01/23/2021
  NobleCon17 Rebroadcast, 01/22/2021
  Why is Bitcoin Plummeting?, 01/22/2021
  Release - Kiromic (KRBP) - Announces the Completion of its GMP Manufacturing Facility in Houston Texas, 01/20/2021
  Release - Palladium One Mining (NKORF)(PDM:CA) - Additional Massive Magmatic Sulphide Intersections at Tyko, 01/19/2021
  Release - CoreCivic (CXW) - Establishes New Reentry-Focused Leadership Role, 01/19/2021
  Small and Microcap Virtual Investor Conferences, 01/17/2021
  Release - GoldHaven Resources (GHVNF)(GOH:CA) - Appoints Chris Ford to GOH Advisory Board for Chilean Operations, 01/15/2021
  Release - CoreCivic (CXW) - To Present At Noble Capital Markets Seventeenth Annual Investor Conference, 01/14/2021
  Release - Energy Fuels (UUUU) - To Present at NobleCon17, 01/14/2021
  Will the US Continue to Subsidize Renewable Energy Projects?, 01/13/2021
  Release - Prophase Labs (PRPH) - To Present at the NobleCon17 Annual Small and Microcap Investor Conference, 01/13/2021
  Release - Jaguar Mining (JAGGF)(JAG:CA) - Reports Fourth Quarter Production With 22532 Gold Ounces , 01/12/2021
  Release - Chakana (CHKKF)(PERU:CA) - Has resumed its 15000m drill program at the Soledad Project in Ancash Peru, 01/12/2021
  Release - Comstock Mining (LODE) - CEO Corrado DeGasperis to Present at NobleCon17, 01/12/2021
  Release - Palladium One Mining (NKORF)(PDM:CA) - More Massive Magmatic Sulphide Intersections, 01/12/2021
  Release - Ely Gold (ELYGF)(ELY:CA) - Closes Railroad-Pinion Royalty Nevada, 01/11/2021
  Release - Helius Medical Technologies (HSDT)(HSM:CA) - Submits Response to U.S. FDA, 01/11/2021
  What Stocks do you Buy When the Dollar Goes Down?, 01/09/2021
  Where Could Investors Profit When the Economy Fully Opens?, 01/08/2021
  Release - Comstock Mining (LODE) - Announces 2020 Achievements Updates Progress, 01/07/2021
  Release - Ely Gold Royalties (ELYGF)(ELY:CA) - Completes Royalty Purchase at Lincoln Hill, 01/07/2021
  How Good are Experts at Predicting the Market?, 01/06/2021
  NobleCon17 Presenting Companies List, 01/06/2021
  Release - Sigyn Therapeutics (SIGY) - Reports Results of Pilot Study to Address Inflammatory CytoVesicles, 01/06/2021
  Release - Palladium One Mining (NKORF)(PDM:CA) - Massive Magmatic Sulphide Discovery at Tyko, 01/05/2021
  The Expected Pace of the IPO Market in 2021, 01/02/2021
  What Should the Price Range Be for Oil and Gas?, 12/31/2020
  What are Stock Market Valuation Indicators Signaling?, 12/29/2020
  Release - U.S. Gold Corp. (USAU) - Drills 244 m of Continuous Mineralization at the CK Gold Project in Wyoming, 12/29/2020
  Release - Slinger Bag (SLBG) - Slinger Bag Announces Successful Uplisting to OTCQB, 12/28/2020
  What Do Investors Look At?, 12/26/2020
  Release - CoreCivic (CXW) - Announces the Sale of 42 Non-Core Government Leased Properties for $106.5 Million, 12/23/2020
  Release - Energy Fuels (UUUU) - Applauds $75 Million Launch of the U.S. Uranium Reserve in Bipartisan 2021 Omnibus Spending Bill, 12/22/2020
  Release - Energy Fuels (UUUU) - Environmental and Social Responsibility Key Priorities for Energy Fuels , 12/21/2020
  Release - Gevo, Inc. (GEVO) - Options Site for Expansion Project, 12/21/2020
  Release - Travelzoo (TZOO) - Wins Best Travel Deals Finder for Ninth Consecutive Year at British Travel Awards, 12/21/2020
  Is the Price of Uranium Rising?, 12/21/2020
  Noble Capital Markets Announces Investor Outreach Campaign for NobleCon Investor Conference, 12/21/2020
  Will Robinhood be Fined on Charges of Gamification?, 12/19/2020
  Release - Avivagen (VIVXF) - Announces Results for Fiscal Year Ending October 31 2020, 12/16/2020
  Release - Chakana (CHKKF)(PERU:CA) - Releases new drill results from four holes at its Paloma West discovery 20201216, 12/16/2020
  Release - Newrange Gold (NRGOF) - Arranges Winter Exploration Program for North Birch Project in Red Lake District, 12/16/2020
  Release - Energy Fuels (UUUU) - Set to Enter Commercial Rare Earth Business in Q1 2021, 12/14/2020
  Rising Oil Prices and Small-Cap Energy Stocks, 12/14/2020
  Why Small Cap Mutual Funds May be the Worst Way to Invest in the Sector, 12/12/2020
  Is a Cure for Diabetes Being Studied?, 12/11/2020
  Release - Gevo, Inc. (GEVO) - Supplies Avfuel with Sustainable Aviation Fuel for Pacific Northwest Region, 12/10/2020
  Release -Sierra Metals Inc. (SMT:CA)(SMTS) - Announces Positive Preliminary Economic Assessment Results Its Cusi Mine, 12/10/2020
  Release - Gevo, Inc. (GEVO) - Dr. Patrick Gruber to Participate in Water Tower Research Fireside Chat Series, 12/10/2020
  Release - Palladium One Mining (NKORF)(PDM:CA) - Discovery Indicates Significant Mineralization Potential at the Disraeli PGE Project, 12/09/2020
  Release - Xenetic Biosciences (XBIO) - Announces Positive Data from Pivotal Phase 3 Clinical Trial Utilizing PolyXen(R) Platform Technology, 12/09/2020
  Release - Brixton Metals Corporation (TSXV: BBB) - Drills 3m At Its Langis Project, 12/08/2020
  Palladium Prices Are Expected to Remain Strong, 12/08/2020
  Release - Golden Predator Mining (NTGSF)(GPY:CA) - The Newfoundland Gold Rush and C2C Gold Corp, 12/08/2020
  Release - Palladium One Mining (NKORF) - Discovers 4 Meters of Massive Magmatic Sulphides Near Surface at Tyko, 12/07/2020
  Release - Global Crossing Airlines Inc. (JETMF)(JET:CA) - Uplists to OTCQB Venture Market, 12/07/2020
  Investment of Excess Corporate Cash, 12/07/2020
  Is Brokerage Consolidation Creating a Need for Equity Research?, 12/05/2020
  Is the Small Firm Effect for Micro Caps Real?, 12/04/2020
  Release - Barksdale Resources (TSXV:BRO)(OTCQX:BRKCF) - Commences Trading On OTCQX, 12/04/2020
  Release - Chakana (CHKKF) - Releases new drill results from four holes at its high-grade copper-gold-silver Paloma West discovery, 12/03/2020
  How Will the RCEP Impact U.S. Oil and Natural Gas?, 12/03/2020
  Release - Palladium One Mining (NKORF) - Receives Additional $5.6 Million From Warrants Exercised, 12/01/2020
  Release - Noble Capital Markets Invites Students to Compete in Second Annual College Challenge, 12/01/2020
  Release - First Vanadium Corp. (TSXV: FVAN) (OTCQX: FVANF) - Drilling Identifies Gold System Stretching 1.4km at Its Gold Target on the Carlin Gold Trend, Nevada, 11/30/2020
  College Scholarships for Esports Gamers, 11/28/2020
  Release - Ceapro Inc. (CRPOF) - Ceapro Inc. Reports 2020 Third Quarter and Nine-Month Financial Results and Operational Highlights, 11/27/2020
  Entrepreneurial Courage and Perseverance Define the Pilgrims, 11/26/2020
  Release - Global Crossing Airlines Inc. (JETMF) - Estimates Delivery of First Cargo Aircraft in June 2021, 11/25/2020
  Release - Energy Fuels (UUUU) - To Present at the H.C. Wainwright Virtual Mining Conference on Monday, November 30 at 3:00 pm ET, 11/24/2020
  Are We Headed to Another Oil Collapse?, 11/24/2020
  Release - Noble Capital Markets, Inc. Announces Type-1 Diabetes Day- The Beginning of the End - Close to a Cure?, 11/23/2020
  College Students are Invited to Show-off Their Company Research Skills to Win, 11/21/2020
  Release - InPlay Oil Corp. (TSX: IPO) (OTCQX: IPOOF) - Announces Participation in Noble Capital Markets Virtual Road Show Series, 11/20/2020
  Release - Lineage Cell Therapeutics (LCTX) - Video - Spinal Cord Injury Update, 11/19/2020
  Will Oil Prices Rise in 2021?, 11/19/2020
  Release - Palladium One Mining (NKORF) - Discovers up to 0.41 Percent Nickel in Boulders and Begins Drill Program at the Tyko Nickel-Copper-PGE Project in Canada, 11/18/2020
  Release - Comstock (LODE) - Announces Positive Nine-months Earnings, 11/17/2020
  Release - Golden Predator (NTGSF, GPY:CA) - Completes 2020 Drill Program at Brewery Creek Mine Yukon , 11/17/2020
  Edge Computing Importance to AI Applications, 11/17/2020
  Release - Cocrystal Pharma (COCP) - Reports Third Quarter 2020 Financial Results and Provides Update on Antiviral Programs, 11/16/2020
  Release - Palladium One Mining (NKORF) - Step-Out Drill Hole Intersects Shallow High-Grade Mineralization at Murtolampi Zone Finland, 11/16/2020
  Release - Cabral Gold (CBGZF, CBR.V) - Announces the Appointment of Carlos Vilhena to Board of Directors, 11/16/2020
  Release - Lineage Cell Therapeutics (LCTX) - Presents New OpRegen Data for Dry AMD With GA at 2020 American Academy of Ophthalmology Annual Meeting, 11/16/2020
  Type-1 Diabetes - The Beginning of the End Close to a Cure, 11/16/2020
  Interest Rates Impact on Investment Sectors, 11/14/2020
  Release - Lineage Cell Therapeutics (LCTX) - Proudly Supports Patients Access To Innovative Cell Therapy Treatments And Research, 11/13/2020
  Will There be Mergers in the Utility Industry?, 11/12/2020
  Release - Newrange Gold (NRGOF) - Updates Drill Program at Pamlio Project, 11/12/2020
  Release - Lineage Cell Therapeutics (LCTX) - Completes Patient Enrollment In Phase 1-2A Clinical Study Of Opregen Cell Therapy, 11/12/2020
  Release - Lineage Cell Therapeutics (LCTX) - Video - Utilizing Pluripotent Stem Cells In Cell Therapy, 11/12/2020
  Strong Third Quarter Performance is Encouraging for Future Performance, 11/11/2020
  Release - Palladium One Mining (NKORF) - Initiates 17500-Meter Phase II Drilling Program in Finland, 11/10/2020
  Release - Chakana (CHKKF) - Announces New High-Grade Discovery at Paloma West - Soledad Project Peru, 11/10/2020
  Release - Cocrystal Pharma (COCP) - Cocrystal Pharma Selected to Present at the World Antiviral Conference, 11/10/2020
  Release - OptimizeRx (OPRX) - Third Quarter 2020 Revenue Up, 11/10/2020
  Release - Gevo (GEVO) - Reports Third Quarter 2020 Financial Results, 11/10/2020
  Release - Sierra Metals Inc. (SMTS) - Reports Record Adjusted Ebitda, 11/09/2020
  Is the Future of Nuclear Power Small Modular Reactors?, 11/09/2020
  Is Gridlock Good for the Stock Market?, 11/07/2020
  Release - U.S. Gold Corp. (USAU) - Provides a PFS Update and Surface Sample Results, 11/05/2020
  Will Solar Panels Continue to Be Subsidized for Households and Businesses?, 11/05/2020
  Release - Energy Fuels (UUUU) - Webcast Postponed to November 4, 2020, 11/04/2020
  The Prolonged Vote Counting Impact on the Stock Market, 11/04/2020
  Release - CoreCivic (CXW) - CoreCivic Reports Third Quarter 2020 Financial Results, 11/04/2020
  Release - Energy Fuels (UUUU) - Produces First Rare Earth Element Concentrate on a Pilot Scale, 11/03/2020
  Release - Outlook Therapeutics (OTLK) - Completes Patient Enrollment of Open-Label Safety Study for ONS-5010 LYTENAVA (bevacizumab-vikg), 11/03/2020
  Release - Ely Gold Royalties (ELYGF) - Purchases Railroad-Pinion Royalty, Nevada, 11/02/2020
  Channelchek News & Research, 11/01/2020
  How to Invest in Esports, 11/01/2020
  How Will Remote Working Change After the Pandemic?, 10/30/2020
  Release - Barksdale Resources Corp. (BRKCF) - Acquires Historic Sunnyside Drill Core, 10/30/2020
  Release - Palladium One Mining (NKORF) - Seeks Trading On OTCQB Venture Market, 10/29/2020
  Which Stocks Do Well After A Presidential Election?, 10/29/2020
  Release - Dyadic (DYAI) - To Report Third Quarter 2020 Financial Results on Thursday November 12, 2020, 10/29/2020
  Release - U.S. Gold Corp. (USAU) - U.S. Gold Corp. Announces Maggie Creek Exploration Update, 10/28/2020
  Release - Comstock (LODE) - Announces Notice of Third Quarter 2020 Results and Business Update Conference Call, 10/27/2020
  Energy M&A Activity Spreads to Canada, 10/27/2020
  Release - Chakana (CHKKF) Reports At Paloma East Soledad Project Peru, 10/26/2020
  Which Media Companies Will Profit From Election Ad Spending?, 10/24/2020
  Smart Money Followers May Have to Work With Less Data, 10/23/2020
  Merger Activity in the Permian is Heating Up - Part Two, 10/22/2020
  Release - Ceapro Inc. (CRPOF) - Announces Increased Financial Contribution from National Research Council of Canada for Innovative PGX Technology Project, 10/22/2020
  Release - Palladium One (NKORF) - Step Out Hole Yields Highest Grades Yet at Kaukua South, 10/22/2020
  Release - Conversion Labs (CVLB) - Appoints Former White House Physician and U.S. Navy Rear Admiral, 10/21/2020
  Release - Canada Nickel - Announces Significant Mineral Resource Update at Crawford Nickel-Cobalt Sulphide Project, 10/21/2020
  Release - CoreCivic (CXW) - Announces Support for Pell Grant Restoration, Voting Rights Restoration and Licensure Reform Policies, 10/21/2020
  Release - Travelzoo (TZOO) - Reports Third Quarter 2020 Results, 10/21/2020
  Release - Sierra Metals - (SMTS) - Announces Positive Preliminary Economic Assessment Results, 10/20/2020
  Release - Palladium One (NKORF) - Discovers 600 m Mineralized Strike Length At Murtolampi, 10/20/2020
  Would Wind Energy Survive Without Subsidies?, 10/20/2020
  Release - Troilus (CHXMF) - Wins Excellence In Sustainable Development Award, 10/20/2020
  Viscount Mining (VLMGF) - Adds Claims At Cherry Creek Property In Nevada, 10/20/2020
  Release - Global Crossing Airlines Signs LOI for Ten (10) A321 Converted Freighters with Vallair, 10/20/2020
  Release - Cocrystal Pharma (COCP) - Cocrystal Pharma Provides Update on Influenza A Program, 10/19/2020
  Release - Troilus Reports Further Results From The Summer 2020 Regional Exploration Program, 10/19/2020
  Fintech Pirates are Looting Unsuspecting Trading Accounts, 10/17/2020
  Release - CoreCivic (CXW) - Announces 2020 Third Quarter Earnings Release And Conference Call Dates, 10/16/2020
  Release - Lineage Cell Therapeutics (LCTX) - Opregen Data Update To Be Featured In Presentation By Christopher D. Riemann, Md, 10/15/2020
  Many Investors Are Keeping Their Powder Dry, 10/15/2020
  Palladium One Mining (NKORF) - A two-minute primer on the LK Project, 10/15/2020
  Release - Sierra Metals (SMTS) Reports Record Third Quarter 2020 Production Results, 10/14/2020
  Release - Newrange Gold (NRGOF) Drills at Pamlico, 10/14/2020
  Release - Ely Gold Royalties (ELYGF) Purchases Trenton Canyon Royalty, Nevada, 10/13/2020
  Oil Demand to Return Soon, 10/13/2020
  Release - Lineage Cell Therapeutics And Cancer Research UK Announce Encouraging Preliminary Phase 1 Study Results, 10/13/2020
  Release - U.S. Gold Corp. (USAU) Issues October 2020 Shareholder Letter, 10/13/2020
  Release - Avivagen (VIVXF) Announces Record Four Tonne Order from UNAHCO, 10/13/2020
  Release - DYAI - Dyadic Updates Market on COVID-19 Initiatives, 10/12/2020
  Is there a Perfect Stock Price?, 10/10/2020
  Oil to Gas Price Ratio: Which Direction is it Headed?, 10/08/2020
  Release - Comstock (LODE) - Mercury Clean Up Pilot Project Commences in Nevada; MCU’s Second Unit Shipped To Philippines, 10/08/2020
  Release - Ely Gold Royalties Options the Aurora West Property, Nevada to Goldcliff Resources, 10/08/2020
  Release - Troilus Discovers New Goldfield Boulder Zone 36 Km from Troilus Mine, 10/08/2020
  Release - Canada Nickel - Final Three Infill Holes Confirm and Extend Higher Grade Mineralization at Crawford Nickel-Cobalt Sulphide Project, 10/08/2020
  Release - Chakana Provides Surface Channel Sampling Results, 10/08/2020
  Release - Discover the potential scale of Kaukua South, 10/07/2020
  Release - Comstock Mining Monetizes Preferred Share Holdings; Reduces Debt by $2 million, 10/06/2020
  Release - Energy Fuels Now Debt-Free; Unique in Uranium Sector, 10/06/2020
  Release - Palladium One step out hole delivers wide, high-grade mineralization at Kaukua South, 10/06/2020
  The Timing of a COVID Vaccine, 10/06/2020
  Release - Chakana Copper To Host Town Hall Webinar, 10/05/2020
  A Feather in the Cap of Robinhood Traders, 10/04/2020
  Release - Cocrystal Pharma Announces Notice of Pendency and Proposed Settlement of Stockholder Derivative Actions, 10/02/2020
  Year-Over-Year Performance at the End of Q3, 10/01/2020
  Release - Energy Fuels Applauds President Trump's Executive Order, 10/01/2020
  Release - Comstock Mining Announces Participation in Noble Capital Markets Virtual Road Show Series, 09/29/2020
  Release - Palladium One Major Discovery Increases Kaukua South Mineralized Strike Length Six-Fold From 600 M to 4 Km, 09/29/2020
  Mergers Within the Energy Industry are Heating Up, 09/29/2020
  Release - Ely Gold Royalties (TSX-V: ELY, OTCQX: ELYGF) Announces Town Hall Webinar, 09/29/2020
  Release - Ely Gold Royalties Purchases Coté Project Gold Royalty, Ontario Canada, 09/29/2020
  Financial Markets Lifted Household Wealth to Record Levels, 09/28/2020
  Release - Golden Predator Commences 2020 Drill Program at Brewery Creek Mine, Yukon, 09/28/2020
  Why Do Small-cap Stocks Outperform After a Major Election?, 09/27/2020
  The Role of Microcap in Tech Future Should Not be Forgotten, 09/25/2020
  Can Tesla Beat Lithium Miners at Their Own Game?, 09/24/2020
  Release - Dyadic and VTT Are Developing an Efficient New Production Method for Covid-19 Vaccines, 09/24/2020
  Have Wind and Solar Energy Made Hydro Irrelevant?, 09/23/2020
  Release - Comstock Mining Launches Geophysical Surveys of the Southern Comstock District, 09/22/2020
  Forty-Year Tax History vs. Current Campaign Promises, 09/22/2020
  Release - Energy Fuels and Team from Penn State University Selected by U.S. Department of Energy, 09/21/2020
  U.S. Debt as a Percentage of GDP Skyrocketing. Should We Be Concerned?, 09/21/2020
  Small-cap Stocks are Looking Better for Investors, 09/19/2020
  Notch Pathway Activation and Severe Cancers, 09/18/2020
  Release - Dyadic Announces Collaboration with Jiangsu Hengrui Medicine for Biologic Drug Development, 09/17/2020
  Release - Comstock Mining Announces New Director; Sets Annual Meeting and Record Dates, 09/16/2020
  Energy Stock Price Moves Have Led to Higher Dividend Yields, 09/16/2020
  Release - Novus Therapeutics Announces Acquisition of Anelixis Therapeutics, 09/15/2020
  Defense Spending in the Crosshairs, 09/15/2020
  Beaver Creek Virtual Summit 2020 Topics of Interest, 09/14/2020
  JOLTS Report Suggests More Risk-Taking, 09/13/2020
  Higher Inventories Cause Large Oil Prices Decline, 09/11/2020
  Tech Companies are Soaring While Retail Stumbles, 09/10/2020
  Release - Comstock Mining Extends Mineral Leases; Secures Strategic Purchase Option, 09/09/2020
  Think You Know Who Will Win the Election? Want to Bet?, 09/09/2020
  It Appears Interest Rates Will Be Lower for Longer, 09/08/2020
  Virtual Conferences are Suddenly Mainstream, 09/07/2020
  Workcations Add a new Class of Traveler, 09/06/2020
  An Opportunity to Ditch Chemotherapy and Still Treat Cancer, 09/04/2020
  Release - Comstock Mining Contracts to Lease and Sell Daney Ranch for $2.7 Million, 09/02/2020
  Is American Energy Dominance Relying on Immaculate Areas?, 09/02/2020
  Release - Golden Predator Acquires 20 Percent of Group 11 Technologies, 09/02/2020
  Are There Looming Challenges For This Emerging Industry?, 09/01/2020
  New SEC Disclosure Requirements on Mining Were Overdue., 08/31/2020
  Release - Palladium One Reports the First Diamond Drill Hole Results to Test the Murtolampi Zone, 08/31/2020
  Release - Cocrystal Pharma Announces Closing of $17.2 Million Bought Deal, 08/31/2020
  The Biggest COVID Winners are in the Business of Making Winners, 08/30/2020
  Hurricane Laura Shut Down Gulf Production with Barely Any Impact on Prices, 08/28/2020
  Do Analyst Price Targets Matter?, 08/26/2020
  Will the COVID Crisis Permanently Change the Way We Work?, 08/25/2020
  Are Mining Companies Facing a Shrinking Opportunity Set?, 08/24/2020
  The Federal Reserve and MIT are Experimenting with Digital Money, 08/22/2020
  SPAC Activity Accelerating in 2020, 08/21/2020
  Release - Ceapro Inc. Reports 2020 Second Quarter and Six-Month Financial Results and Operational Highlights, 08/20/2020
  Natural Gas Storage Imbalances and Higher prices, 08/20/2020
  Release - Gevo Exceeds $1.5B in Long-Term Revenue Contracts with Signing of Trafigura, 08/20/2020
  Release - A Marketing Services Company that Investors May be Overlooking, 08/19/2020
  Natural Gas Has a Sizeable Energy Role that is Waning, 08/18/2020
  Release - Ceapro Inc. Provides Update on Development of an Inhalable Therapeutic for COVID-19, 08/18/2020
  Release - Jaguar Mining Reports Updated Mineral Reserves and Mineral Resources for the Pilar Mine, Brazil as at May 31, 2020, 08/18/2020
  Release - Comstock Mining Announces Full Second Quarter 2020 Results, 08/17/2020
  Eliminating the Con-Fusion, 08/17/2020
  Investing and Trading Skills, 08/16/2020
  OPEC Forecasts Lower Demand as Output Cuts Taper, 08/14/2020
  Release - InPlay Oil Corp. Announces BDC Term Facility and Provides Second Quarter 2020 Financial and Operating Results, 08/14/2020
  Release - Aurania Resources - Keith Barron’s Straight Talk on Mining Series: Module 1 - Epithermal Gold-Silver Deposits, 08/14/2020
  Advertising Budgets are Going Where the Eyes Are, 08/13/2020
  Release - Sierra Metals Reports Solid Consolidated Financial Results For The Second Quarter Of 2020, Despite Covid-19 Interruptions, 08/13/2020
  Release - Dyadic Announces Second Quarter 2020 Results and Highlights Recent Company Progress, 08/13/2020
  Canadian Oil Production Drops To the Lowest Level Since 2016, 08/12/2020
  Release - Comstock Mining Extinguishes Senior Secured Debenture Via Favorable Refinancing, 08/12/2020
  Fear of Missing Out on Owning the Next Apple?, 08/11/2020
  Large Oil Companies Had a Good Run, are We Witnessing the End of an Era?, 08/10/2020
  Expect 500,000 Fewer U.S. Births Next Year, 08/09/2020
  Release - Cocrystal Pharma Reports Second Quarter 2020 Financial Results and Provides Updates on Antiviral Programs, 08/06/2020
  Utility Allowed ROE and Premium Lag, 08/06/2020
  Investors Should Pay More Attention to A-T-M Offerings?, 08/05/2020
  Release - Cocrystal Pharma Announces Publication of Positive Data Demonstrating Potent In Vitro Inhibition Against Coronavirus, 08/04/2020
  Unexpected Lower Oil Inventories are a Dent in the Upward Trend, 08/04/2020
  Release - Ceapro Inc. Announces Publication of Positive Results from Study Evaluating Avenanthramides in Exercise-Induced Inflammation, 08/04/2020
  Virtual Investor Day 2020, 08/04/2020
  A Kodak Moment - Shares Rose as Much as 650 Percent, 08/03/2020
  Channelchek Experiences Meteoric Activity Increase, 08/01/2020
  Ecommerce Adapts While In-Person Retail Struggles, 07/31/2020
  What’s Corporate America’s “Fair Share” of Taxes?, 07/30/2020
  Investors Looking Beyond Lower Expectations, 07/29/2020
  Is $40 the sweet spot for sweet crude?, 07/28/2020
  Release - Sierra Metals Announces Restart Of Production At Its Cusi Silver Mine, Mexico, 07/28/2020
  Release - Helix BioPharma Virtual Town Hall 2020-07-29, 07/28/2020
  Will 2020 Go Down as the Year of the SPAC?, 07/27/2020
  Trading vs Investing vs Tomorrow, 07/26/2020
  PSCs Can Function Like Embryonic Stem Cells, 07/24/2020
  Is M and A Picking Up in The Energy Sector?, 07/23/2020
  Will Digital Media And Technology Stocks Take A Breather?, 07/22/2020
  Podcast and Audio Platforms are Becoming Valuable Properties, 07/21/2020
  NIH Awards Research Grant for Diabetes Gene Therapy Technology Licensed by Genprex, 07/21/2020
  U.S. Rare Earth Mining gets Boost from Government, 07/20/2020
  Why “News Investors” Outperform the News Reporters, 07/19/2020
  AI and Skyborg Technology Will Create Huge Tech Winners, 07/17/2020
  SIERRA METALS REPORTS SOLID SECOND QUARTER 2020 PRODUCTION RESULTS, 07/16/2020
  Covid-19 May be Killing the U.S. LNG Market, 07/16/2020
  Sierra Metals Reports Solid Second Quarter 2020 Production Results - Video Presentation, 07/16/2020
  Is the TV Rollup Strategy Over?, 07/15/2020
  DLH Announces Executive Appointments, 07/15/2020
  Palladium One Resumes Drilling at The Läntinen Koillismaa PGE-Cu-Ni Project in Finland, 07/14/2020
  Can One “Do Good” and “Do Well” in Tandem?, 07/13/2020
  Equity Markets Give a Lesson in Behavioral Psychology, 07/12/2020
  The Risk of Economic Confidence Waning, 07/10/2020
  Warren Buffet vs. Elon Musk: Who’s Right?, 07/09/2020
  Analyzing Text to Predict Market Volatility, 07/08/2020
  Carbon-Free Nuclear Energy Expectations Through 2050, 07/07/2020
  Energy Sector in Rapidly Growing Indonesia, 07/06/2020
  Covid-19, Scary vs. Dangerous, 07/05/2020
  Amazon Prime Video’s Move To Go Linear, 07/02/2020
  More Accurate than Polls to Gauge Election Outcomes, 07/01/2020
  Virtual Roadshows Are the New Normal, 07/01/2020
  Raw Materials and the Scalability of Tesla’s Vision, 06/29/2020
  Copying the Brightest Investment Ideas, 06/28/2020
  The Next Round of Stimulus and Industries Impacted, 06/26/2020
  Onconova Therapeutics Announces Participation In Noble Capital Markets Investor Webinar, 06/24/2020
  Virtual Power Plants and Tesla Car Batteries, 06/22/2020
  Will There be an Explosion of New Acquisitions?, 06/20/2020
  Sierra Metals Confirms New High-Grade Silver Zone At Its Cusi Mine, Mexico, Including 17 Meters True-Width Of 428 Grams Per Ton Silver, And Provides An Operational Update, 06/19/2020
  Weaning America Off Unemployment Insurance, 06/19/2020
  Is Elon Musk’s “Battery Day” Losing its Charge?, 06/17/2020
  The Limits of Government Economic Tinkering, 06/13/2020
  Gold is the New Green, 06/12/2020
  Are Individual Investors The “Smart Money”, 06/10/2020
  Restaurants Post-Lockdown Look Good!, 06/09/2020
  Genprex Scheduled to Join Russell 3000 Index, 06/09/2020
  Channelchek C-Suite Interview Series, 06/08/2020
  Alternative Investments and 401(k) Plans, 06/06/2020
  The Supply of Cash and Stock Prices, 06/05/2020
  Should The Stock Market Be Up Double-Digits On The Year?, 06/04/2020
  Today's Feature, 05/31/2020
  Which Major Index Outperforms in June?, 05/29/2020
  Ceapro Inc. Reports 2020 First Quarter Financial Results and Highlights, 05/28/2020
  Trading Technology Continues to Level the Playing Field for Investors, 05/28/2020
  How Do Negative Interest Rates Impact Households?, 05/22/2020
  The New Age of Investor Relations, 05/21/2020
  Lower Multiples are a Good Case for Utility Investing, 05/21/2020
  The Russell Index Reconstitution, What we Expect, 05/20/2020
  Millennials Could Use Help With Investing, 05/15/2020
  The Fed’s Power and Impact are Again Tested, 05/14/2020
  Feds Bond ETF Purchases will Impact Equity Investors, 05/12/2020
  Berkshire Hathaway 2020 Annual Meeting Full Transcript and Video, 05/08/2020
  Climbing a “Wall of Worry”, 05/07/2020
  The Correlation of Passive Ownership and Underperformance, 05/05/2020
  Ely Gold Royalties Announces CAN$10,000,000 Brokered Private Placement, 05/04/2020
  Gaining More Clarity and Broadening Investment Options, 05/01/2020
  “Words of Wisdom” Awaited - Berkshire Hathaway Annual Meeting, 04/30/2020
  Small-Cap vs. Large-Cap Investing , 04/29/2020
  Companies Developing a Treatment for COVID-19 , 04/28/2020
  Covid-19 Vaccination Update, 04/24/2020
  Contango and the Known Risk to ETFs, 04/24/2020
  Investors should look beyond the headline but be aware of the bigger implications, 04/23/2020
  What Now? Post-Pandemic Stock Market Investing, 04/22/2020
  Noble Capital Markets Analyst Profile - Naureen Quibria, Ph.D., 04/20/2020
  Why Index Funds Could be a Mistake in 2020, 04/20/2020
  Noble Capital Markets Analyst Profile - Poe Fratt, 04/20/2020
  Noble Capital Markets Analyst Profile - Michael Heim, 04/20/2020
  Noble Capital Markets Analyst Profile - Joe Gomes, 04/20/2020
  Noble Capital Markets Analyst Profile - Mark Reichman, 04/20/2020
  Noble Capital Markets Analyst Profile - Michael Kupinski, 04/20/2020
  Noble Capital Markets Analyst Profile - Robert LeBoyer, 04/20/2020
  Michael Burry says COVID-19 Cure Worse than the Disease, 04/17/2020
  Has the Race for a Treatment Been Won?, 04/17/2020
  Stock Index Adjustments and Self-Directed Investors, 04/16/2020
  Ceapro Inc. Reports Fourth Quarter and Full Year 2019 Results and Highlights, 04/16/2020
  PDS Biotechnology Initiates Novel Vaccine Development Programs For COVID-19 and Universal Influenza; Delay of PDS0101 VERSATILE-002 trial, 04/16/2020
  Lowering Economic activity and Trickle Down, 04/09/2020
  Rearview Mirror Measurements in Economics, 04/09/2020
  The Case for Silver, 04/08/2020
  Should Economic Aid Target Businesses or Individuals and Families?, 04/07/2020
  Where Investors Found Double-Digit Growth in Q1, 04/03/2020
  Should Equity Markets Close for the Pandemic?, 04/03/2020
  Unemployment – how high can it go?, 04/01/2020
  Is There a Gold Lining Among These Clouds?, 03/31/2020
  A Significant Indicator of the Fed’s Resolve, 03/27/2020
  Xenetic Biosciences, Inc. Reports 2019 Year End Results and Provides Corporate Update, 03/27/2020
  Curbside Financial Advisors, 03/27/2020
  Denominators, Disease and Death, 03/26/2020
  How Your Business Can Satisfying the Current Need for Content, 03/24/2020
  COVID-19 Spread and Threat, 03/23/2020
  Capitalism Versus Coronavirus, 03/20/2020
  COVID-19, Where we are Right Now, 03/20/2020
  Factors to Consider when Setting a New Investment Course, 03/20/2020
  Here’s Your Stimulus Check, Now What?, 03/18/2020
  Portfolio Diversification May Reduce Volatility and Enhance Investment Returns , 03/17/2020
  ZIRP (Zero Interest Rate Policy) and QE5, 03/16/2020
  Bear Market Cycles, Is it “Different” this Time?, 03/13/2020
  Where Do Americans get Information for their Biggest Decisions?, 03/11/2020
  Is This the Bottom of the Barrel?, 03/10/2020
  Do Market Scares Provide Uncommon Opportunity?, 03/10/2020
  Does the Fed Have the Tools to Beat Forecasted Weakness, 03/06/2020
  Additional Balance in 60-40 Asset Mixes, 03/06/2020
  Why Gold Could Retain its Luster , 03/05/2020
  Market Selloffs and IRA Contributions , 03/02/2020
  The Business of Mass-Producing Vaccines, 03/02/2020
  Will the Stock Market Survive COVID-19, 02/26/2020
  Opportunity Zone Investment Funds Provide a Triple Tax Break, 02/25/2020
  Noble Capital Markets 2020 Investor Conference - a Huge Success, 02/20/2020
  Is the Market Disregarding Earnings Results?, 02/14/2020
  Renaissance in Inflammasome Therapeutics , 02/14/2020
  Free Markets, National Security, Global Competition, and 5G, 02/13/2020
  Valentine’s Day by the Numbers, 02/13/2020
  What Investors Should Know About Cannabis Stocks in 2020, 02/07/2020
  Containing Coronavirus has Caused an “Oil Demand Shock” , 02/05/2020
  Thirty-Something Homeownership has Declined, Have Millennials Given Up?, 02/03/2020
  The Investor Conference at the Guitar Hotel in Florida offers More than New Ideas, 01/31/2020
  The Quick Spread of Coronavirus is Impacting Global Economies and Markets , 01/29/2020
  Impact Investing Challenges Traditional Methods for Promoting Social Good, 01/27/2020
  Fin Tech is one of the Fastest Growing Tech Sectors, 01/22/2020
  Do Budget Deficits Matter? U.S. Deficit Tops $1 Trillion in First 11 Months of Fiscal Year, 01/17/2020
  Jeb Bush to Present at NobleCon16 Investor Conference , 01/17/2020
  Investment Barriers Once Seen as Insurmountable are Falling Fast, 01/17/2020
  Cobalt and Rare Earth Metals from the Ocean floor Eyed to Meet Growing Battery Demand, 01/14/2020
  Whatever Happened to the Appalachia Shale Gas Boom?, 01/13/2020
  Is a Cure for Type 1 Diabetes Imminent?, 01/10/2020
  Ari Fleischer to Present at NobleCon16 Investor Conference, 01/08/2020
  Long Term Investors and Small Cap Stocks, 01/07/2020
  Can Algorithmic Trading Continue to Expand?, 01/06/2020
RESEARCH Reports
  Endeavour Silver (EXK)(EDR:CA) - Endeavour Builds Metals Inventory For Sale At Higher Prices, 04/09/2021
  CoreCivic, Inc. (CXW) - A Deal Can Be Done, But At What Cost?, 04/08/2021
  Great Lakes Dredge & Dock (GLDD) - A Win on Marsh Creation in Louisiana, 04/08/2021
  The GEO Group, Inc. (GEO) - Suspends Dividend Evaluating Corporate Structure, 04/08/2021
  Kelly Services Inc. (KELYA) - Expands IT Staffing Capabilities with Acquisition of Softworld, 04/07/2021
  Palladium One Mining Inc. (NKORF)(PDM:CA) - Exploration Activities Accelerate at the Tyko Nickel-Copper Project, 04/07/2021
  Bassett Furniture (BSET) - Strong 1Q21 Results, 04/06/2021
  Kratos Defense and Security (KTOS) - More Positive Data Points, 04/06/2021
  One Stop Systems Inc. (OSS) - First Award Under New AI Transportables Target, 04/06/2021
  Industry Report - Metals and Mining First Quarter 2021 Review and Outlook, 04/05/2021
  Industry Report - Energy - Where Is The Supply Response?, 04/05/2021
  Golden Predator Mining (NTGSF)(GPY:CA) - Moving Right Along, 04/05/2021
  Harte-Hanks Inc. (HRTH) - Raising Price Target Shifting More Attention Toward Growth, 04/01/2021
  Endeavour Silver (EXK)(EDR:CA) - Executive Transition Plans Assure Continued Progress and Growth, 03/31/2021
  Grindrod Shipping (GRIN) - Asset Sales Enhance Dry Bulk Exposure - Raising Price Target, 03/31/2021
  Pyxis Tankers Inc. (PXS) - Refinancing Done. Shifting to Growth, 03/31/2021
  Schwazze (SHWZ) - Reports 4Q20 and Full Year Results, 03/31/2021
  Seanergy Maritime (SHIP) - Another Acquisition Increases Leverage - Upgrading to Outperform, 03/31/2021
  Helius Medical Technologies (HSDT)(HSM:CA) - FDA Approval of PoNS for MS, 03/29/2021
  QuoteMedia (QMCI) - Margins Take A Hit As Revenues Ramp, 03/29/2021
  Allegiant Gold Allegiant Gold Ltd (AUXXF)(AUAU:CA) - Virtual Road Show Take-Aways, 03/26/2021
  FAT Brands Inc. (FAT) - Solid 4Q as Operations Continue to Rebound, 03/26/2021
  One Stop Systems Inc. (OSS) - Steadily Improving Operating Environment, 03/26/2021
  Chakana Copper Corp (CHKKF)(PERU:CA) - Drilling at Huancarama Reveals Second High-Grade Discovery, 03/25/2021
  Indonesia Energy Corp (INDO) - Rating Upgraded, PO Reinstated, 03/25/2021
  Pyxis Tankers Inc. (PXS) - Weak End to 2020, But Capital Raises Add Flexibility, 03/25/2021
  Seanergy Maritime (SHIP) - 4Q2020 Results In Line. Expanding for Upturn, 03/25/2021
  Helius Medical Technologies (HSDT)(HSM:CA) - Helius Medical - An Innovative Approach to Neurostimulation, 03/24/2021
  Comstock Mining (LODE) - First Mercury Remediation System is Up and Running in the Philippines, 03/24/2021
  InPlay Oil (IPOOF)(IPO:CA) - Price Object More Than Doubles With Many Factors Improving, 03/24/2021
  Newrange Gold (NRGOF)(NRG:CA) - A Multi-Million Ounce Gold Resource in the Making at Pamlico?, 03/24/2021
  Energy Fuels (UUUU)(EFR:CA) - Energy Fuels Restocks its Balance Sheet and Inventories, 03/23/2021
  Great Lakes Dredge & Dock (GLDD) - Added Awards Announced, 03/23/2021
  Eagle Bulk Shipping (EGLE) - ATM Program and Selling Triggered After Strong Stock Move, 03/22/2021
  Great Lakes Dredge & Dock (GLDD) - A Good Win in Alabama, 03/22/2021
  Sierra Metals (SMTS)(SMT:CA) - Solid 2020 Performance 2021 Estimates Largely Unchanged, 03/22/2021
  Harte-Hanks Inc. (HRTH) - Getting Its Act Together, 03/19/2021
  Palladium One Mining Inc. (NKORF)(PDM:CA) - Methodical Approach to Exploration Yielding Positive Outcomes, 03/19/2021
  Seanergy Maritime (SHIP) - Staying on Growth Path With Two New Acquisitions, 03/19/2021
  Sierra Metals (SMTS)(SMT:CA) - Solid 2020 Operational and Financial Results Growth Outlook Remains Favorable, 03/19/2021
  Endeavour Silver (EXK)(EDR:CA) - Sale of El Cubo Mine Expected to Close by Month-End, 03/18/2021
  Euroseas Ltd. (ESEA) - Higher Rate Charters Boost 2021 EBITDA and Price Target, 03/18/2021
  Gevo, Inc. (GEVO) - Looking Beyond Losses to Brighter Future, 03/18/2021
  InPlay Oil (IPOOF)(IPO:CA) - Strong Quarter. Stronger 2021 Outlook, 03/18/2021
  Travelzoo (TZOO) - The Skies Are Looking Friendlier, But, 03/18/2021
  Pangaea Logistics Solutions Ltd. (PANL) - Solid Finish to 2020 and New Year Starting on Good Note, 03/17/2021
  Townsquare Media Inc (TSQ) - Leaning In With A Digital First Strategy, 03/17/2021
  Eagle Bulk Shipping (EGLE) - Firm Market Drives Price Target Higher Again, 03/15/2021
  Information Services (III) - Additional 4Q Comments and Updated Projections, 03/15/2021
  Comstock Mining (LODE) - Taking Stock of 2020 and Looking Ahead, 03/12/2021
  Information Services (III) - Better than Expected 4Q20 Results, 03/12/2021
  Lineage Cell Therapeutics (LCTX) - Q4 2020 EPS: Catalysts Rich 2021 Ahead, 03/12/2021
  Comtech (CMTL) 2Q21 - Results Ahead of Plan, but Full Year 2021 Expectations Unchanged, 03/12/2021
  Entravision Communications Corporation - (EVC) A Remarkable Quarter Raising Price Target, 03/12/2021
  Palladium One Mining Inc. (NKORF)(PDM:CA) - Accelerating Progress on Multiple Fronts, 03/12/2021
  Bassett Furniture (BSET) - Orders Continue to be Strong Raising PT, 03/11/2021
  Great Lakes Dredge & Dock (GLDD) - A Nice Win on Boston Harbor, 03/11/2021
  PDS Biotechnology Corp (PDSB) - Versamune-based COVID-19 Vaccine Consortium Received Brazilian Government Grant, 03/11/2021
  InPlay Oil (IPOOF)(IPO:CA) - Estimates Raised to Reflect New Price Deck, 03/10/2021
  Sierra Metals (SMTS)(SMT:CA) - Copper Prices Strengthen in 2021 Updating Estimates, 03/10/2021
  Pangaea Logistics Solutions Ltd. (PANL) - Well-timed Acquisitions Expand Fleet At Opportune Time, 03/10/2021
  Eagle Bulk Shipping (EGLE) - Strong Start Sets Positive Path For New Year, 03/08/2021
  1-800-Flowers.com (FLWS) - Are Investors Underestimating This Ecommerce Play?, 03/08/2021
  Avivagen Inc. (VIVXF)(VIV:CA) - First Quarter 2021 Results, 03/05/2021
  Comstock Mining (LODE) - Comstock Transforms Its Business Model to Accelerate Growth, 03/05/2021
  Eagle Bulk Shipping (EGLE) - Impressive Forward Cover Drives Price Target Higher, 03/05/2021
  Salem Media (SALM) - A Rush To Fill A Void, 03/05/2021
  Seanergy Maritime (SHIP) - Offering Funds Cape Acquisition and Reduces Debt, 03/05/2021
  Golden Predator Mining (NTGSF)(GPY:CA) - Is the Whole Greater than the Sum of its Parts?, 03/04/2021
  One Stop Systems Inc. (OSS) - Raises $10 Million in Direct Offering, 03/04/2021
  Schwazze (SHWZ) - Completes Star Buds Acquisition, 03/04/2021
  ACCO Brands Corporation (ACCO) - Note Offering, 03/03/2021
  Energy Fuels (UUUU)(EFR:CA) - Rare Earth Element Outtake Agreement Signed. Is This Just The Beginning?, 03/03/2021
  Indonesia Energy Corp (INDO) - Rating downgraded with shares above our price target, 03/03/2021
  Pyxis Tankers Inc. (PXS) - Capital Raises Expand Public Market Float and Enhance Financial Flexibility, 03/03/2021
  Vectrus (VEC) - Solid 4Q20 and FY2020 Even in Face of COVID, 03/03/2021
  1-800-Flowers.com (FLWS) - In The League Of Leading Ecommerce Companies, 03/02/2021
  Aurania Resources (AUIAF)(ARU:CA) - Forging Ahead Virtual Investor Update on March 3, 03/02/2021
  E.W. Scripps Company (SSP) - Several Surprising Comments On The Investor Call, 03/02/2021
  Endeavour Silver (EXK)(EDR:CA) - Full Year 2020 Net Income Above Expectations, 03/02/2021
  Kratos Defense & Security (KTOS) - A Deeper Dive into 2020 Results, 03/02/2021
  Avivagen Inc. (VIVXF)(VIV:CA) - Initiation Coverage of Avivagen: Well positioned Early Stage Ag-biotech Company, 03/01/2021
  CoreCivic, Inc. (CXW) - Now the US Marshals Service?, 03/01/2021
  Genco Shipping & Trading Limited (GNK) - A Solid Finish to 2020 and Good Start to 2021, 03/01/2021
  Grindrod Shipping (GRIN) - 2H2020 Results Below Expectations But Transitioning to More Positive Outlook, 03/01/2021
  Euroseas Ltd. (ESEA) - Solid Operating Results - Outlook Remains Favorable, 02/26/2021
  Gray Television Inc. (GTN) Outlook A Solid Start To The Year, 02/26/2021
  Kratos Defense & Security (KTOS) - 4Q20 Results In-line, 02/26/2021
  Orion Group Holdings (ORN) - Better-than-Expected Quarter, But Flat Year Ahead?, 02/26/2021
  Ely Gold Royalties (ELYGF)(ELY:CA) - Cimarron Option Agreement with Crestview Holds Promise, 02/25/2021
  Onconova Therapeutics Inc. (ONTX) - Positive Trajectory Raising Price Target, 02/25/2021
  Palladium One Mining Inc. (NKORF)(PDM:CA) - Momentum Builds in 2021, 02/25/2021
  Orion Group Holdings (ORN) - Results Should Reinforce Favorable Outlook, 02/24/2021
  Allegiant Gold Allegiant Gold Ltd (AUXXF)(AUAU:CA) - Executing According to Plan, 02/24/2021
  Cumulus Media Inc. (CMLS) - In A Good Spot, 02/24/2021
  Newrange Gold (NRGOF)(NRG:CA) - Drilling Reveals New High-Grade Mineralization Near the Merritt Zone, 02/24/2021
  Lineage Cell Therapeutics (LCTX) - OPC1 Investor and Analyst Day Overview, 02/23/2021
  PDS Biotechnology Corp (PDSB) - Manufacturing Partner Added to Consortium to Commercialize Coronavirus Vaccine in Latin America, 02/23/2021
  Gevo, Inc. (GEVO) - Today's Update Should Highlight Upcoming Milestones, 02/23/2021
  Kelly Services Inc. (KELYA) - Raising to Outperform on Positive Trends Favorable Risk Reward, 02/22/2021
  One Stop Systems Inc. (OSS) - Moving to Market Perform on Price Appreciation, 02/22/2021
  QuoteMedia (QMCI) - Setting The Table For A Strong 2021, 02/22/2021
  The GEO Group, Inc. (GEO) - Tapping Market for $200 Million in Exchangeable Bonds, 02/22/2021
  Capstone Turbine (CPST) - Coverage Initiated on Capstone Turbine, 02/19/2021
  Coeur Mining (CDE) 2020 Earnings Lower Than Expected Updating Estimates, 02/19/2021
  Great Lakes Dredge & Dock (GLDD) - A Softer End to Year But Positive Outlook Intact, 02/19/2021
  ACCO Brands Corporation (ACCO) - Post Call Commentary, 02/18/2021
  Aurania Resources (AUIAF)(ARU:CA) - Initial Vicus Project Concessions Awarded in Peru, 02/18/2021
  E.W. Scripps Company (SSP) - A Triton Haul, 02/18/2021
  enCore Energy Corp. (ENCUF)(EU:CA) - Price Objective Raised With Plans Progressing. Are Uranium Prices Strengthening?, 02/18/2021
  Energy Services of America (ESOA) - Increasing Price Target to Reflect Multiple Expansion, 02/18/2021
  EuroDry Ltd. (EDRY) - Firmer Dry Bulk Market Drives Up Price Target, 02/18/2021
  Tribune Publishing Company (TPCO) - Rating Changed To Underperform Dropping Coverage, 02/18/2021
  ACCO Brands Corporation (ACCO) - Fourth Quarter Results In-line with Estimates, 02/17/2021
  Esports Entertainment Group, Inc. (GMBL) - Putting The Pieces Together, 02/17/2021
  The GEO Group, Inc. (GEO) - Better Than Expected 4Q, 02/17/2021
  Tribune Publishing Company (TPCO) - Alden Bucks Up, 02/17/2021
  Pyxis Tankers Inc. (PXS) - Strong Price Performance Shifts Risk Reward Profile, 02/17/2021
  Chakana Copper Corp (CHKKF)(PERU:CA) - Drilling Activity to Accelerate in 2021, 02/16/2021
  Ely Gold Royalties (ELYGF)(ELY:CA) - Ely Gold Reveals Rare Earths Potential of its El Campo Property in California, 02/16/2021
  Great Lakes Dredge & Dock (GLDD) - Quarterly Call Will Reinforce January NobleCon17 Appearance, 02/16/2021
  E.W. Scripps Company (SSP) - Insights On the Upcoming Quarter Raising Price Target, 02/12/2021
  Eagle Bulk Shipping (EGLE) - Fleet Renewal Program Twists Toward Growth, 02/12/2021
  CoreCivic, Inc. (CXW) - Solid Fourth Quarter Buried Under the Noise, 02/11/2021
  Ely Gold Royalties (ELYGF)(ELY:CA) - Increasing Its Stake in Nevada's Hog Ranch Gold Project, 02/11/2021
  Comtech (CMTL) - Awarded $235.7 Million Contract from U.S. Army, 02/10/2021
  Golden Predator Mining (NTGSF)(GPY:CA) - Bankable Feasibility Study Expected Later This Quarter, 02/10/2021
  Neovasc (NVCN)(NVCN:CA) - Complied with Nasdaq Minimum Bid Price Requirement, 02/10/2021
  Aurania Resources (AUIAF)(ARU:CA) - Tiria-Shimpia Silver-Gold Target in the Crosshairs, 02/09/2021
  Lineage Cell Therapeutics (LCTX) - Transformation on Track, Reiterating Outperform Rating, 02/09/2021
  Newrange Gold (NRGOF)(NRG:CA) - Making Significant Progress on Two Fronts, 02/09/2021
  Schwazze (SHWZ) - Adds Two More Star Buds Locations Five To Go, 02/08/2021
  Comtech (CMTL) - New Awards Piling Up Encouraging Signs of Positive Business Momentum, 02/04/2021
  DLH Holdings Corp. (DLHC) - Post Call Commentary, 02/04/2021
  Esports Entertainment Group, Inc. (GMBL) - Raising Price Target; Closes In On Acquisitions, 02/04/2021
  PDS Biotechnology Corp (PDSB) - NCI-sponsored Phase 2 Study will Progress to Full Enrollment, 02/04/2021
  Bassett Furniture (BSET) - Furniture on Sale Initiating Coverage on Bassett Furniture, 02/03/2021
  DLH Holdings Corp. (DLHC) - Solid 1Q21 Results But COVID Still Impacting, 02/03/2021
  Cumulus Media Inc. (CMLS) - What Does A Transitional Year Mean?, 02/02/2021
  Gray Television Inc. (GTN) - Plenty Of Room For Acquisition Fueled Growth, 02/02/2021
  Seanergy Maritime (SHIP) - New Time Charters Should Lower Volatility, 02/02/2021
  Aurania Resources (AUIAF)(ARU:CA) - Mobile MT Geophysical Survey Providing A Clearer Picture, 02/01/2021
  Euroseas Ltd. (ESEA) - Container Market Strength Drives Price Target Higher, 02/01/2021
  Grindrod Shipping (GRIN) - Year Off to Positive Start, 02/01/2021
  1-800-Flowers.com (FLWS) - At Some Point This Will Happen, 01/29/2021
  Ayala Pharmaceuticals (AYLA) - First Patient Dose in Breast Cancer Trial, 01/29/2021
  Eagle Bulk Shipping (EGLE) - Adding Another Ultramax, 01/29/2021
  Endeavour Silver (EXK)(EDR:CA) - Updating Estimates based on 2021 Production and Cost Guidance, 01/29/2021
  Gevo, Inc. (GEVO) - Update on Timing of FEED Engineering and Financial Close, 01/28/2021
  Tribune Publishing Company (TPCO) - What Is The Company's Value?, 01/28/2021
  Allegiant Gold Allegiant Gold Ltd (AUXXF) - 2021 Expected to Be Catalyst Rich, 01/27/2021
  CoreCivic, Inc. (CXW) - Biden Signs Executive Order to End Use of Private Prisons by BoP, 01/27/2021
  Entravision Communications Corporation (EVC) - A Surprising Value For Its Digital Businesses, 01/27/2021
  The GEO Group, Inc. (GEO) - Biden Signs Executive Order to End Use of Private Prisons by BoP, 01/27/2021
  Chakana Copper Corp (CHKKF) - Connecting the Dots at Huancarama, 01/26/2021
  CoreCivic, Inc. (CXW) - NobleCon17 Presentation, 01/26/2021
  EuroDry Ltd. (EDRY) - NobleCon 17 Presentations Highlight Favorable Outlook, 01/26/2021
  Gevo, Inc. (GEVO) - Fire Side Chat Complements NobleCon 17 Presentation, 01/26/2021
  The GEO Group, Inc. (GEO) - Dinner with CFO Brian Evans and EVP Corporate Relations Pablo Paez, 01/26/2021
  Golden Predator Mining (NTGSF)(GPY:CA) - Drill Program Results Checking the Boxes, 01/26/2021
  Pyxis Tankers Inc. (PXS) - NobleCon 17 Presentation Reinforces Positive LT Outlook, 01/26/2021
  Salem Media (SALM) - A Focus On Digital, 01/26/2021
  Townsquare Media Inc (TSQ) - Raising The Price Target Again. What Is The Excitement About?, 01/26/2021
  DLH Holdings Corp. (DLHC) - NobleCon17 Review, 01/25/2021
  ACCO Brands Corporation (ACCO) - CEO Boris Elisman at NobleCon17, 01/25/2021
  Aurania Resources (AUIAF)(ARU:CA) - Geophysical Survey Yielding Significant Data to Inform Drilling, 01/25/2021
  Ayala Pharmaceuticals (AYLA) - Noblecon17 Presentation Emphasizes the Positive Trajectory and the Upcoming Catalysts, 01/25/2021
  Comtech (CMTL) - NobleCon17 Presentation, 01/25/2021
  Eagle Bulk Shipping (EGLE) - Year Off to Good Start - Flat Water and Blue Sky?, 01/25/2021
  Euroseas Ltd. (ESEA) - NobleCon 17 Presentation Highlights Strong Container Market, 01/25/2021
  FAT Brands Inc. (FAT) - FAT Brands at NobleCon17, 01/25/2021
  Gevo, Inc. (GEVO) - Significant Capital Raises Boost Financing Visibility, 01/25/2021
  Great Lakes Dredge & Dock (GLDD) - NobleCon17 Presentation Highlights Positive Dredging Outlook, 01/25/2021
  Genco Shipping & Trading Limited (GNK) - Positive Trends Highlighted at NobleCon17, 01/25/2021
  Information Services (III) - NobleCon17 Observations, 01/25/2021
  One Stop Systems Inc. (OSS) - Commentary from NobleCon17, 01/25/2021
  Palladium One Mining Inc. (NKORF)(PDM:CA) - Hitting on All Cylinders, 01/25/2021
  Pangaea Logistics Solutions Ltd. (PANL) - NobleCon 17 Presentations Reinforce Positive Trends, 01/25/2021
  Schwazze (SHWZ) - Sit Down With CEO Justin Dye, 01/25/2021
  Seanergy Maritime (SHIP) - NobleCon 17 Presentation Highlights Solid Start to Year, 01/25/2021
  Sierra Metals (SMTS)(SMT:CA) - Fourth Quarter and Full Year 2020 Production Results; Updating Estimates, 01/25/2021
  Orion Group Holdings (ORN) - Conference Highlights Positives - New Concrete Awards, 01/22/2021
  Lineage Cell Therapeutics (LCTX) - CFO Left Reiterating Outperform Rating, 01/21/2021
  Orion Group Holdings (ORN) - Conference Presentation Should Highlight Favorable Outlook, 01/19/2021
  Gevo, Inc. (GEVO) - Conference Presentation Should Highlight Significant Progress, 01/18/2021
  Ely Gold Royalties (ELYGF)(ELY:CA) - Lincoln Hill and Railroad Pinion Royalty Acquisitions Closed, 01/15/2021
  Ceapro (CRPOF)(CZO:CA) - Business Update: Positive Trajectory Continues, 01/14/2021
  InPlay Oil (IPOOF)(IPO:CA) - Capital Budget and Guidance In Line With Expectations, 01/14/2021
  Newrange Gold (NRGOF)(NRG:CA) - Gaining Traction, 01/14/2021
  Seanergy Maritime (SHIP) - Debt Refinancings Completed and Impact is Favorable, 01/14/2021
  Industry Report - Digital, Media and Entertainment Industry - Are We There Yet?, 01/12/2021
  Endeavour Silver (EXK)(EDR:CA) - Increasing Estimates Based on Improved Mine Performance, 01/12/2021
  Information Services (III) - Raising PT As Share Price Continues Upward Trajectory, 01/12/2021
  Sierra Metals (SMTS)(SMT:CA) - Sierra Metals Puts Itself in Play Updating Estimates, 01/12/2021
  Great Lakes Dredge and Dock (GLDD) - New Awards of $61 Million - Increasing Price Target, 01/12/2021
  Comstock Mining (LODE) - Building Blocks for Increasing Shareowner Value, 01/08/2021
  One Stop Systems Inc. (OSS) - Another Contract Win Raising Price Target, 01/08/2021
  Chakana Copper Corp (CHKKF) - A Unique Gold and Copper Opportunity Unfolding in Peru, 01/07/2021
  enCore Energy Corp. (ENCUF)(EU:CA) - enCore Closes Westwater Resources Asset Acquisition, 01/06/2021
  Energy Services of America (ESOA) - FY2020 Earnings Revised Higher Due to Stimulus Legislation, 01/06/2021
  Palladium One Mining Inc. (NKORF)(PDM:CA) - Tyko Drilling Program Yielding Exciting Results, 01/06/2021
  Industry Report - Energy - 2020-4Q Review and Outlook, 01/05/2021
  Ayala Pharmaceuticals (AYLA) - Pivotal Desmoid Tumor Trial is Set to Initiate in H1 2021, 01/05/2021
  Gevo, Inc. (GEVO) - Two milestones in a week - FEED Engineering firm identified, 01/05/2021
  Vectrus (VEC) - A Busy Holiday Period for Vectrus Another Acquisition, 01/05/2021
  Industry Report - Metals and Mining Fourth Quarter 2020 Review and Outlook, 01/04/2021
  Helix Biopharma (HBPCF)(HBP:CA) - Q1 F2021 Business Update, 01/04/2021
  Tribune Publishing Company (TPCO) - Are You Serious?, 01/04/2021
  Gevo, Inc. (GEVO) - Debt free with higher pro forma cash balance moving into 2021, 12/31/2020
  Vectrus (VEC) - Another Major Win: OMDAC-SWACA Award, 12/31/2020
  Indonesia Energy Corp (INDO) - Shares surge 47 percent on rising oil prices, 12/31/2020
  Eagle Bulk Shipping (EGLE) - Another Ultramax Acquisition Adds to Fleet Renewal, 12/30/2020
  Vectrus (VEC) - Zenetex Acquisition Expands and Deepens Offerings, 12/30/2020
  Genco Shipping & Trading Limited (GNK) - Asset Swap Enhances Fleet Profile Without Capital Outlay, 12/29/2020
  CoreCivic, Inc. (CXW) - Sale of 42 Non-Core Properties Yields $27 million for Debt Reduction, 12/24/2020
  Eagle Bulk Shipping (EGLE) - Fleet Renewal Continues and Equity Offering Completed, 12/24/2020
  Ely Gold Royalties (ELYGF)(ELY:CA) - The Company You Keep, 12/23/2020
  Gevo, Inc. (GEVO) - Greenfield Site Announced - Debt Free One Way or Another, 12/22/2020
  Golden Predator Mining (NTGSF)(GPY:CA) - Waiting for the Bankable Feasibility Study?, 12/22/2020
  Onconova Therapeutics Inc. (ONTX) - Phase 1 Trial Commencement for CDK4 6 ARK5 Program in H1 2021, Rating Raised, 12/22/2020
  Schwazze (SHWZ) - Half A Hit Is Better Than No Hit At All Closes On Six Star Buds Locations, 12/22/2020
  Euroseas Ltd. (ESEA) - Another Fixture Beats Expectations on Rate and Term, 12/22/2020
  Genprex (GNPX) - REQORSA Manufacturing is Scaled Up for Clinical Testing, 12/22/2020
  Gevo, Inc. (GEVO) - More Clarity on First Project. Debt Free Heading into 2021, 12/21/2020
  Coeur Mining (CDE) - The Story Is Growing Stronger, 12/18/2020
  enCore Energy Corp. (ENCUF)(EU:CA) - Coverage Initiated As Outperform to Ride Uranium Price Wave, 12/18/2020
  Orion Group Holdings (ORN) - Two Marine Awards for $20 million. Program Sales Initiated, 12/18/2020
  Eagle Bulk Shipping (EGLE) - Shifting to Growth?, 12/17/2020
  Esports Entertainment Group, Inc. (GMBL) - Acquisition Improves Its Hand, 12/17/2020
  Energy Services of America (ESOA) - Acquisition Adds Confidence to FY2021 Outlook, 12/17/2020
  Gray Television Inc. (GTN) - A Peachy Political Outlook, 12/17/2020
  Tribune Publishing Company (TPCO) - Building A Large Cash Hoard, 12/17/2020
  Townsquare Media Inc (TSQ) - Why We Are Raising Estimates And Price Target?, 12/16/2020
  Allegiant Gold Ltd (AUXXF) - Fashioning Nevada's Eastside Project Into A Multi-Million Ounce Gold Resource, 12/15/2020
  Ely Gold Royalties (ELYGF)(ELY:CA) - Executes Option Agreement to Sell Weepah Closes Acquisition of Watershed Royalty, 12/15/2020
  Energy Fuels (UUUU)(EFR:CA) - Line of Sight Toward Commercial Mixed REE Production Investor Webcast on December 15, 12/15/2020
  Energy Services of America (ESOA) - PPP tax payment masks strong quarter and profitable year, 12/14/2020
  FAT Brands Inc. (FAT) - FAT Brands, Fog Cutter Merger Announced Increasing PT, 12/14/2020
  Aurania Resources (AUIAF)(ARU:CA) - Solid Progress, 12/11/2020
  Indonesia Energy Corp (INDO) - Delay to Drilling Start May Be a Good Thing With Rising Oil Prices, 12/11/2020
  Great Lakes Dredge & Dock (GLDD) - Cant Win Them All - Houston Move Creates Some Turnover, 12/10/2020
  Comtech Telecommunications Corporation (CMTL) - 1Q Results Beat Expectations But COVID Impacts Continue, 12/10/2020
  Kratos Defense & Security (KTOS) - $37.7 million Skyborg Award, 12/09/2020
  DLH Holdings Corp. (DLHC) - Covid Continues to Impact Revenues But Well Positioned Going Forward, 12/08/2020
  Palladium One Mining Inc. (NKORF)(PDM:CA) - Tyko Nickel Project Drilling Program Yields Success, 12/08/2020
  Great Lakes Dredge and Dock (GLDD) - Offshore Wind Plans Drive Expansion of Fleet Renewal, 12/07/2020
  Schwazze (SHWZ) Historic - Vote, But What Does it Mean?, 12/07/2020
  Vectrus (VEC) - New Business Momentum Continuing, 12/07/2020
  Ayala Pharmaceuticals (AYLA) - Top NOTCH Targeting for Broad Oncology Indications, Initiating Coverage at Outperform, 12/02/2020
  Newrange Gold (NRGOF)(NRG:CA) - Recent Drilling Reveals a New Gold Zone at Pamlico, 12/02/2020
  Euroseas Ltd. (ESEA) - Higher Rates on New Fixtures Boost EBITDA Estimates, 12/01/2020
  Gevo, Inc. (GEVO) - Upcoming Milestones - Increasing Price Target, 11/30/2020
  Aurania Resources (AUIAF)(ARU:CA) - Work Advances at Tsenken Investor Call Scheduled for December 1st, 11/27/2020
  Comtech Telecommunications Corporation (CMTL) - Another Major NG911 Win, 11/25/2020
  Kelly Services Inc. (KELYA) - Expands Into Higher Education with Acquisition of Greenwood Asher Associates, 11/25/2020
  Schwazze (SHWZ) - Schwazze: Building a Seed to Sale Colorado Powerhouse, 11/24/2020
  Euroseas (ESEA) - Soft 3Q2020 But Container Market Fundamentals Improving, 11/23/2020
  Pyxis Tankers Inc. (PXS) - Lowering EBITDA Estimate to Reflect 3Q2020 and Soft Outlook, 11/23/2020
  When Will Western Canadian Oil Producers Improve Cash Flow?, 11/23/2020
  Esports Entertainment Group, Inc. (GMBL) - Heightened M&A Activity In The Gambling Space Validates ESports Strategy, 11/20/2020
  Great Lakes Dredge & Dock (GLDD) - Largest Award Ever On Horizon, 11/19/2020
  Lineage Cell Therapeutics (LCTX) - Takeaways from Expert call on OpRegen, 11/19/2020
  Palladium One Mining Inc. (NKORF)(PDM:CA) - Another Important Element to the Story, 11/19/2020
  Seanergy Maritime (SHIP) - Improved Quarter, But Refinancing Risk Remains High, 11/19/2020
  Esports Entertainment Group, Inc. (GMBL) - Building a Sturdy Foundation Esports Business, 11/18/2020
  Seanergy Maritime (SHIP) - Upcoming 3Q2020 Call Will Focus on Dry Bulk Market and Debt Refinancing, 11/18/2020
  Comstock Mining (LODE) - Solid Execution, 11/18/2020
  Cocrystal Pharma Inc. (COCP) - Q3 EPS Pipeline Remains on Track, 11/17/2020